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Engineering | School of Biological and Health Systems Engineering

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Date(s) - 09/17/2021
3:05 pm - 4:05 pm


Developing Multi-faceted Tools to Probe Tissue Function for Precision Medicine

Xiling Shen, Ph.D.
Associate Professor in the Department of Biomedical Engineering at Duke University

Date: Friday, September 17, 2021
Time: 3:05 p.m.
Location: SCOB 228

Seminar Flier


Bodily cells undergo transformations in space and time during development, disease progression, and therapeutic treatment. A holistic approach that combines engineering tools, patient-derived models, and analytical methods is needed to map cellular reprogramming and expose new therapeutic opportunities. The talk will cover our effort across the entire spectrum from bench to bedside, including miniature organoid technology to guide clinical precision- and immune-oncology, targeting epigenetic and metabolic reprogramming of cancer metastasis, algorithms to identify cancer microbiome, and tracking organogenesis during embryonic development.


Dr. Shen is the Hawkins Family Associate Professor in the Department of Biomedical Engineering at Duke University. He is also the director of the Woo Center for Big Data and Precision Health. He received his BS, MS, and PhD degrees from Stanford University and the NSF career award at Cornell University. He is the steering committee chair of the NCI Patient-Derived Model of Cancer Consortium and chair of the NCI Tissue Engineering Consortium 2021 conference. His lab studies precision medicine from a systems biology perspective. Areas of interests include cancer, stem cells, the but-brain axis, and infectious diseases.