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Engineering | School of Biological and Health Systems Engineering

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Date/Time
Date(s) - 10/01/2021
3:05 pm - 4:05 pm

Category(ies)


Designer peptide-based biomaterials

Speaker:

Vivek A. Kumar, Ph.D.
Assistant Professor in Biomedical Engineering and Chemical Engineering, New  Jersey Institute of Technology, and Restorative Dentistry (Rutgers)

Date: Friday, October 1, 2021
Time: 3:05 p.m.
Location: SCOB 228

Seminar Flier

Abstract

Self-assembling peptide hydrogels (SAPH) are a class of injectable scaffolds that present a paradigm in drug development and biomaterials. Facile self-assembly of monomeric/ multi-meric constituents result in high epitope presentation of biological signals. Persistent signaling, in situ bolus delivery and demonstrable modification to actuate specific biological responses allow development of novel classes of biomaterials that behave as scaffolds and drugs. This presentation will describe a few examples of novel peptide-biomaterial drugs that are capable of site-specific delivery to tissue, potentiating numerous tissue remodeling responses:

  • Tissue regeneration/ revascularization
  • Drug delivery
  • IGF driven diabetic fracture healing
  • COVID therapeutics

A focus is also made to describe entrepreneurship and innovation helping bridge the gap between academia, industry and clinical medicine.

BioSketch

Vivek Kumar received his bachelor’s degree in biomedical engineering from Northwestern University in 2006, and doctorate degree in biomedical engineering from the Georgia Institute of Technology in 2011. He did post-doctoral work at BIDMC, Harvard Medical School, and Rice University. He has honed his expertise is in the area of tissue engineering, drug development and delivery, and specific research interests are in the area of inflammation modulation and angiogenesis, especially in understanding the role of small growth factor or cytokine mimics’ ability to signal biological processes. He is the co-author of over 40 peer-reviewed journal articles, over 4 dozen abstracts, an inventor on a dozen patents/applications, and serial entrepreneur (3 startups to-date).

Vivek currently serves at the New Jersey Institute of Technology as an Assistant Professor in Biomedical Engineering and Chemical Engineering, and at the Rutgers School of Dental Medicine. Vivek teaches Biomaterials and Biomedical Translation and Entrepreneurship. As a pre-health advisor and a member of the BME Faculty search committee, University IP committee, and endowed fellow of the Albert Dorman Honors College, Vivek strives to encourage research involvement with undergraduates, graduates and post-doctoral scientists. Research in the KumarLab (kumarlab.njit.edu) aims at translating technologies in startups (NangioTx.com / SAPHTx.com) towards treating a wide array of pathologies. To this end, Vivek is a frequent member of SBIR/STTR and NIH study sections, and serves as a reviewer for over a dozen peer-reviewed journals. Made it this far into this abstract – check out our latest start-up in a completely different space – Parking! (pullup.io)